STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0121Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 76.03; identified by sequence similarity; putative. (368 aa)    
Predicted Functional Partners:
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
    
   0.816
TM_0547
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 67.00; identified by sequence similarity; putative.
    
 0.586
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.545
TM_0122
Ferric uptake regulation protein; Similar to PID:511113 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the Fur family.
       0.456
TM_0123
Zinc ABC transporter, periplasmic zinc-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Metal-binding component; Belongs to the bacterial solute-binding protein 9 family.
       0.456
TM_0124
Zinc ABC transporter, ATP-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Probably responsible for energy coupling to the transport system.
       0.456
TM_0125
Zinc ABC transporter, permease protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal; Belongs to the ABC-3 integral membrane protein family.
       0.456
TM_0126
Response regulator; Similar to GB:M16775 SP:P13792 GB:X67676 PID:143328 PID:143330 percent identity: 60.09; identified by sequence similarity; putative.
       0.456
TM_0127
Sensor histidine kinase; Similar to PID:2352098 percent identity: 54.13; identified by sequence similarity; putative.
       0.456
TM_1269
Biotin synthetase, putative; Required for the maturation of the [FeFe]-hydrogenase HydA (By similarity). Catalyzes the reductive cleavage of S-adenosyl-L- methionine (in vitro), suggesting it may contribute to the biosynthesis of an essential sulfur-containing ligand that binds to the hydrogenase active site [2Fe-2S] cluster. Belongs to the radical SAM superfamily. HydE family.
    
 0.423
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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