STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0122Ferric uptake regulation protein; Similar to PID:511113 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the Fur family. (121 aa)    
Predicted Functional Partners:
TM_0124
Zinc ABC transporter, ATP-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Probably responsible for energy coupling to the transport system.
  
  
 0.882
TM_0125
Zinc ABC transporter, permease protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal; Belongs to the ABC-3 integral membrane protein family.
 
  
 0.879
TM_0123
Zinc ABC transporter, periplasmic zinc-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Metal-binding component; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.867
TM_0126
Response regulator; Similar to GB:M16775 SP:P13792 GB:X67676 PID:143328 PID:143330 percent identity: 60.09; identified by sequence similarity; putative.
  
  
 0.817
TM_0127
Sensor histidine kinase; Similar to PID:2352098 percent identity: 54.13; identified by sequence similarity; putative.
     
 0.814
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.623
TM_1515
Ferric uptake regulation protein; Similar to PID:1652859 percent identity: 59.70; identified by sequence similarity; putative; Belongs to the Fur family.
  
     0.560
TM_0807
Alkyl hydroperoxide reductase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.545
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.457
TM_0121
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 76.03; identified by sequence similarity; putative.
       0.456
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.