Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
TM_0123Zinc ABC transporter, periplasmic zinc-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Metal-binding component; Belongs to the bacterial solute-binding protein 9 family. (267 aa)    
Predicted Functional Partners:
TM_0124
Zinc ABC transporter, ATP-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Probably responsible for energy coupling to the transport system.
 
 
 0.999
TM_0125
Zinc ABC transporter, permease protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal; Belongs to the ABC-3 integral membrane protein family.
 
 
 0.999
TM_0122
Ferric uptake regulation protein; Similar to PID:511113 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the Fur family.
 
  
 0.864
TM_0127
Sensor histidine kinase; Similar to PID:2352098 percent identity: 54.13; identified by sequence similarity; putative.
  
  
 0.820
TM_0126
Response regulator; Similar to GB:M16775 SP:P13792 GB:X67676 PID:143328 PID:143330 percent identity: 60.09; identified by sequence similarity; putative.
     
 0.817
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.617
rpmB
Ribosomal protein L28; Similar to GB:AE000657 percent identity: 78.95; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.588
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.514
TM_0121
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 76.03; identified by sequence similarity; putative.
       0.456
TM_0510
Iron-dependent transcriptional repressor, putative; Similar to GP:2624310 percent identity: 62.63; identified by sequence similarity; putative.
  
 
 0.444
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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