node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TM_0356 | TM_1374 | TM_0356 | TM_1374 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | 0.991 |
TM_0356 | TM_1400 | TM_0356 | TM_1400 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | 0.993 |
TM_0356 | glyA | TM_0356 | TM_0720 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.993 |
TM_0356 | trpA | TM_0356 | TM_0137 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.992 |
TM_0356 | trpB1 | TM_0356 | TM_0138 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.995 |
TM_0356 | trpB2 | TM_0356 | TM_0539 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.991 |
TM_0356 | trpC | TM_0356 | TM_0140 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Indole-3-glycerol phosphate synthase; Similar to SP:Q56319 PID:1333731 GB:AE000512 percent identity: 99.60; identified by sequence similarity; putative; Belongs to the TrpC family. | 0.569 |
TM_0356 | trpF | TM_0356 | TM_0139 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Phosphoribosylanthranilate isomerase; Similar to PID:1054860 SP:Q56320 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative. | 0.431 |
TM_0356 | trpGD | TM_0356 | TM_0141 | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | Anthranilate synthase component II; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.470 |
TM_1374 | TM_0356 | TM_1374 | TM_0356 | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | 0.991 |
TM_1374 | TM_1400 | TM_1374 | TM_1400 | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | 0.991 |
TM_1374 | glyA | TM_1374 | TM_0720 | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.992 |
TM_1374 | trpB1 | TM_1374 | TM_0138 | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.991 |
TM_1400 | TM_0356 | TM_1400 | TM_0356 | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | 0.993 |
TM_1400 | TM_1374 | TM_1400 | TM_1374 | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | 0.991 |
TM_1400 | glyA | TM_1400 | TM_0720 | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.994 |
TM_1400 | trpA | TM_1400 | TM_0137 | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.991 |
TM_1400 | trpB1 | TM_1400 | TM_0138 | Aspartate aminotransferase, putative; Involved in the degradation of L-serine via 3- hydroxypyruvate. Catalyzes the transamination between L-serine and pyruvate to yield 3-hydroxypyruvate and alanine. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.991 |
glyA | TM_0356 | TM_0720 | TM_0356 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase catabolic; Similar to GB:M21312 SP:P05792 GB:X14430 PID:147923 PID:43043 percent identity: 74.37; identified by sequence similarity; putative. | 0.993 |
glyA | TM_1374 | TM_0720 | TM_1374 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoglycerate mutase; Similar to GB:AE000657 percent identity: 62.38; identified by sequence similarity; putative; Belongs to the phosphoglycerate mutase family. | 0.992 |