STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0156Alkaline phosphatase; Similar to SP:P19405 GB:M33634 PID:551721 PID:1945090 GB:AL009126 percent identity: 58.53; identified by sequence similarity; putative; Belongs to the alkaline phosphatase family. (434 aa)    
Predicted Functional Partners:
thiDN
Conserved hypothetical protein; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. In the C-terminal section; belongs to the ThiN family.
    
 0.997
secA
Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
    
 
 0.837
tig
Trigger factor, putative; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
    
 
 0.821
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.683
TM_1264
Phosphate ABC transporter, periplasmic phosphate-binding protein; Similar to GB:AE000782 percent identity: 58.70; identified by sequence similarity; putative.
  
  
 0.569
TM_0250
DNA processing chain A; Similar to GB:L42023 SP:P43862 PID:1006171 PID:1221098 PID:609332 percent identity: 61.21; identified by sequence similarity; putative.
 
    0.559
TM_0157
Actinorhodin polyketide dimerase-related protein; Similar to GB:X63449 PID:46811 SP:Q02058 percent identity: 50.34; identified by sequence similarity; putative.
       0.538
TM_1621
Hypothetical protein; Identified by sequence similarity; putative.
  
 
 0.500
TM_0041
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to GB:D26185 SP:P29252 PID:467468 GB:AL009126 percent identity: 65.87; identified by sequence similarity; putative.
     
 0.477
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
  
 0.412
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.