STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rex1Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (208 aa)    
Predicted Functional Partners:
TM_0170
Hypothetical protein; Identified by sequence similarity; putative.
       0.810
TM_0171
Conserved hypothetical protein; Similar to SP:P54452 PID:1303787 GB:AL009126 percent identity: 52.08; identified by sequence similarity; putative.
       0.810
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.810
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
       0.810
hppA
Pyrophosphatase, proton-translocating; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
       0.810
leuS
leucyl-tRNA synthetase; Similar to PID:1652380 percent identity: 69.10; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.801
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.701
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
    0.641
TM_0176
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 58.27; identified by sequence similarity; putative.
       0.632
TM_0166
Folylpolyglutamate synthase/dihydrofolate synthase; Similar to GB:L04520 SP:Q05865 PID:142936 PID:1119198 GB:AL009126 percent identity: 57.76; identified by sequence similarity; putative; Belongs to the folylpolyglutamate synthase family.
     
 0.588
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.