Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0182Conserved hypothetical protein; Similar to GB:L77117 PID:1592124 percent identity: 64.76; identified by sequence similarity; putative. (397 aa)    
Predicted Functional Partners:
TM_0181
Hypothetical protein; Identified by sequence similarity; putative.
       0.817
glmM
Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
       0.817
TM_0183
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.72; identified by sequence similarity; putative.
       0.815
TM_0180
Hypothetical protein; Identified by sequence similarity; putative.
       0.550
TM_0894
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57744 PID:1591018 percent identity: 52.76; identified by sequence similarity; putative.
  
     0.526
TM_1265
Conserved hypothetical protein; Similar to GB:L77117 PID:1500537 percent identity: 50.36; identified by sequence similarity; putative.
  
     0.489
TM_1166
Oxygen-independent coproporphyrinogen III oxidase, putative; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
  
 0.409
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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