STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0195Guanosine pentaphosphate phosphohydrolase, putative; Similar to GB:AE000511 PID:2313368 percent identity: 49.63; identified by sequence similarity; putative. (288 aa)    
Predicted Functional Partners:
TM_0729
(p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.993
TM_0196
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 70.91; identified by sequence similarity; putative.
       0.577
TM_0193
Conserved hypothetical protein; Similar to GB:U00096 SP:P77307 PID:1773173 PID:1786699 percent identity: 58.13; identified by sequence similarity; putative.
       0.477
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.467
TM_0194
ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 61.24; identified by sequence similarity; putative.
       0.463
TM_1078
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 65.74; identified by sequence similarity; putative.
  
 
  0.449
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.431
TM_1330
lacI family transcriptional regulator, putative; Similar to GB:L77117 PID:1590997 percent identity: 70.37; identified by sequence similarity; putative.
  
   
 0.407
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.