STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0202Hypothetical protein; Identified by sequence similarity; putative. (300 aa)    
Predicted Functional Partners:
TM_0203
ABC transporter, permease protein, cysTW family; Similar to PID:2440148 percent identity: 50.22; identified by sequence similarity; putative.
 
 0.988
TM_0204
ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 68.28; identified by sequence similarity; putative.
 
 0.968
TM_0201
NADP-reducing hydrogenase, subunit D, putative; Similar to GB:U07229 PID:466366 percent identity: 69.31; identified by sequence similarity; putative.
 
  
 0.830
TM_0483
ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 66.35; identified by sequence similarity; putative.
 
 0.784
TM_0485
ABC transporter, permease protein, cysTW family; Similar to GB:L42023 PID:1003598 PID:1222281 PID:1204605 SP:Q57306 percent identity: 52.16; identified by sequence similarity; putative.
  
 0.784
TM_0403
Nitrogen regulatory protein P-II; Similar to GP:2735324 percent identity: 69.64; identified by sequence similarity; putative; Belongs to the P(II) protein family.
    
 
 0.743
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.609
TM_0198
ATP-dependent Clp protease, ATPase subunit; Similar to PID:1001492 percent identity: 74.36; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family.
       0.585
disA
Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.
       0.585
TM_1426
Fe-hydrogenase, subunit alpha; Similar to GP:2865517 percent identity: 100.00; identified by sequence similarity; putative.
 
  
 0.564
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.