STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0203ABC transporter, permease protein, cysTW family; Similar to PID:2440148 percent identity: 50.22; identified by sequence similarity; putative. (243 aa)    
Predicted Functional Partners:
TM_0204
ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 68.28; identified by sequence similarity; putative.
 
 0.991
TM_0202
Hypothetical protein; Identified by sequence similarity; putative.
 
 
 0.980
TM_0483
ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 66.35; identified by sequence similarity; putative.
 
 0.908
TM_0201
NADP-reducing hydrogenase, subunit D, putative; Similar to GB:U07229 PID:466366 percent identity: 69.31; identified by sequence similarity; putative.
    
 0.761
TM_0484
Pyrimidine precursor biosynthesis enzyme, putative; Similar to SP:P42883 SP:P43534 SP:P47183 PID:1015913 PID:1302455 percent identity: 52.16; identified by sequence similarity; putative.
 
 
 0.736
TM_0198
ATP-dependent Clp protease, ATPase subunit; Similar to PID:1001492 percent identity: 74.36; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family.
       0.586
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.585
disA
Conserved hypothetical protein; Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.
       0.585
TM_1432
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 54.61; identified by sequence similarity; putative.
    
 0.402
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.