STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub- subfamily. (319 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Similar to GB:L77117 PID:1500502 percent identity: 61.52; identified by sequence similarity; putative.
  
 0.998
TM_0273
Fructose-bisphosphate aldolase; Similar to GB:AE000657 percent identity: 78.33; identified by sequence similarity; putative.
  
 
 0.996
pfp
6-phosphofructokinase, pyrophosphate-dependent; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II s [...]
  
  
0.993
tal
Transaldolase-related protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.993
TM_0736
Mannose-6-phosphate isomerase; Similar to GB:U02562 SP:P39841 PID:1129073 PID:476092 GB:AL009126 percent identity: 56.25; identified by sequence similarity; putative.
 
  
 0.992
TM_1762
Transketolase, putative; Similar to GP:452486 percent identity: 53.52; identified by sequence similarity; putative.
  
 
 0.992
TM_0296
Fructokinase; Similar to PID:1052973 percent identity: 57.14; identified by sequence similarity; putative.
  
 
 0.991
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
  
  
 0.990
TM_0828
Sugar kinase, pfkB family; Similar to SP:P11099 GB:X14827 PID:46605 percent identity: 54.05; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
  
  
 0.989
pyk
Pyruvate kinase; Similar to GB:AL009126 percent identity: 64.53; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
 
 
 0.964
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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