Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0223Conserved hypothetical protein; Similar to GB:D26185 SP:P37557 PID:467448 GB:AL009126 percent identity: 70.00; identified by sequence similarity; putative. (77 aa)    
Predicted Functional Partners:
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.887
rplQ
Ribosomal protein L17; Similar to GB:AE000511 SP:P56042 PID:2314458 percent identity: 64.96; identified by sequence similarity; putative.
   
 
 0.844
rpmB
Ribosomal protein L28; Similar to GB:AE000657 percent identity: 78.95; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.840
TM_0363
Fibronectin-binding protein, putative; Similar to GB:AL009126 percent identity: 53.99; identified by sequence similarity; putative.
  
 
 
 0.834
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.831
rpmA
Ribosomal protein L27; Similar to GB:D13267 SP:P02427 PID:216637 PID:606123 GB:U00096 percent identity: 75.00; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL27 family.
    
 
 0.829
rplT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).
   
   0.829
hslO
Conserved hypothetical protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
  
 0.827
rpmF
Ribosomal protein L32; Similar to GB:AE000657 percent identity: 72.41; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family.
    
   0.825
rpmG
Ribosomal protein L33; Similar to SP:P35873 GB:Z11839 PID:407022 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.825
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.