STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0224biotin--(acetyl-CoA carboxylase) synthetase; Similar to GB:AE000666 percent identity: 57.33; identified by sequence similarity; putative. (231 aa)    
Predicted Functional Partners:
TM_1269
Biotin synthetase, putative; Required for the maturation of the [FeFe]-hydrogenase HydA (By similarity). Catalyzes the reductive cleavage of S-adenosyl-L- methionine (in vitro), suggesting it may contribute to the biosynthesis of an essential sulfur-containing ligand that binds to the hydrogenase active site [2Fe-2S] cluster. Belongs to the radical SAM superfamily. HydE family.
  
 
 0.994
TM_0717
propionyl-CoA carboxylase, gamma subunit; Similar to GP:2706400 percent identity: 51.91; identified by sequence similarity; putative.
 
 
 0.977
TM_0716
propionyl-CoA carboxylase, beta subunit; Similar to PID:1177652 SP:P53003 percent identity: 76.31; identified by sequence similarity; putative.
 
 
 0.960
bioY
bioY protein; Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex. Probably a biotin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (Probable).
 
   
 0.707
TM_0798
Malonyl CoA-acyl carrier protein transacylase; Similar to SP:P71019 PID:1502420 GB:AL009126 percent identity: 64.24; identified by sequence similarity; putative.
 
   
 0.657
TM_0225
1-aminocyclopropane-1-carboxylate deaminase, putative; Similar to SP:Q00740 PID:150963 percent identity: 55.14; identified by sequence similarity; putative; Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
       0.597
TM_0802
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
   
 0.587
TM_0226
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 65.58; identified by sequence similarity; putative.
       0.580
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.573
TM_0715
tRNA nucleotidyl transferase-related protein; Similar to GB:AE000657 percent identity: 56.71; identified by sequence similarity; putative; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.572
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.