STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0230Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.78; identified by sequence similarity; putative. (158 aa)    
Predicted Functional Partners:
TM_0229
Conserved hypothetical protein; Similar to GB:L77117 PID:1591686 percent identity: 52.10; identified by sequence similarity; putative.
       0.810
TM_0228
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 72.27; identified by sequence similarity; putative.
   
   0.639
TM_0159
Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.569
TM_0715
tRNA nucleotidyl transferase-related protein; Similar to GB:AE000657 percent identity: 56.71; identified by sequence similarity; putative; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.513
TM_0370
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 92.41; identified by sequence similarity; putative; Belongs to the UPF0273 family.
  
     0.460
TM_1235
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 77.64; identified by sequence similarity; putative.
  
     0.433
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.