STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%). (403 aa)    
Predicted Functional Partners:
pduL
Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
   
 0.999
acyP
Acylphosphatase, putative; Similar to GB:AE000782 percent identity: 69.66; identified by sequence similarity; putative.
     
 0.992
pta
Phosphate butyryltransferase; In addition to acetyl-CoA (100%), the enzyme accepts propionyl-CoA (60%) and butyryl-CoA (30%); Belongs to the phosphate acetyltransferase and butyryltransferase family.
 
 
 0.970
TM_1755
Phosphate butyryltransferase; Similar to GB:L14744 PID:457633 percent identity: 63.01; identified by sequence similarity; putative.
 
 0.874
TM_0273
Fructose-bisphosphate aldolase; Similar to GB:AE000657 percent identity: 78.33; identified by sequence similarity; putative.
  
  
 0.857
TM_0272
Pyruvate,orthophosphate dikinase; Similar to PID:854265 percent identity: 75.17; identified by sequence similarity; putative; Belongs to the PEP-utilizing enzyme family.
    
 0.776
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
  
 
 0.726
TM_0275
Transcriptional regulator, GntR family; Similar to GB:AL009126 percent identity: 54.00; identified by sequence similarity; putative.
   
 
 0.722
TM_0268
5-methyltetrahydrofolate S-homocysteine methyltransferase; Similar to GB:U00017 PID:466997 percent identity: 54.29; identified by sequence similarity; putative.
     
 0.632
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
  
 
 0.578
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.