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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0275Transcriptional regulator, GntR family; Similar to GB:AL009126 percent identity: 54.00; identified by sequence similarity; putative. (340 aa)    
Predicted Functional Partners:
TM_1856
Transcriptional regulator, LacI family; Similar to GB:AL009126 percent identity: 52.02; identified by sequence similarity; putative.
  
     0.774
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%).
   
 
 0.722
TM_0273
Fructose-bisphosphate aldolase; Similar to GB:AE000657 percent identity: 78.33; identified by sequence similarity; putative.
   
 
 0.707
TM_0272
Pyruvate,orthophosphate dikinase; Similar to PID:854265 percent identity: 75.17; identified by sequence similarity; putative; Belongs to the PEP-utilizing enzyme family.
  
    0.505
TM_0114
Sugar ABC transporter, periplasmic sugar-binding protein; Similar to SP:P36949 GB:Z25798 PID:397499 PID:1894757 GB:AL009126 percent identity: 51.00; identified by sequence similarity; putative.
 
 
 0.459
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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