STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0290Citrate synthase; Similar to GB:AE000782 percent identity: 66.39; identified by sequence similarity; putative; Belongs to the citrate synthase family. (367 aa)    
Predicted Functional Partners:
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
  
 0.983
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
     
 0.980
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
  
 0.970
TM_1148
Isocitrate dehydrogenase; Similar to SP:P21954 PID:1431074 PID:171749 percent identity: 74.63; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.961
pta
Phosphate butyryltransferase; In addition to acetyl-CoA (100%), the enzyme accepts propionyl-CoA (60%) and butyryl-CoA (30%); Belongs to the phosphate acetyltransferase and butyryltransferase family.
  
 
 0.960
porC
Pyruvate ferredoxin oxidoreductase, gamma subunit; Similar to PID:2052278 GB:AE000512 percent identity: 99.53; identified by sequence similarity; putative.
     
 0.957
porD
Pyruvate ferredoxin oxidoreductase, delta subunit; Similar to GP:1197392 percent identity: 100.00; identified by sequence similarity; putative.
     
 0.957
porA
Pyruvate ferredoxin oxidoreductase, alpha subunit; Similar to GP:2052279 percent identity: 100.00; identified by sequence similarity; putative.
     
 0.957
porB
Pyruvate ferredoxin oxidoreductase, beta subunit; Similar to PID:1197393 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
     
 0.957
TM_0405
Keto/oxoacid ferredoxin oxidoreductase, beta subunit, putative; Similar to GB:L77117 PID:1591241 percent identity: 69.14; identified by sequence similarity; putative.
     
 0.957
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (22%) [HD]