Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0298Alcohol dehydrogenase, zinc-containing; Similar to GB:U14003 SP:P39400 PID:537201 GB:U00096 PID:1790819 percent identity: 51.23; identified by sequence similarity; putative. (317 aa)    
Predicted Functional Partners:
TM_0297
Oxidoreductase, short chain dehydrogenase/reductase family; Similar to SP:P50167 PID:763164 percent identity: 59.92; identified by sequence similarity; putative.
 
 
 0.854
TM_0436
Alcohol dehydrogenase, zinc-containing; Similar to PIR:S34613 percent identity: 51.75; identified by sequence similarity; putative.
  
     0.773
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
  
 0.699
TM_0296
Fructokinase; Similar to PID:1052973 percent identity: 57.14; identified by sequence similarity; putative.
  
 
 0.601
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
  
  
 0.561
tal
Transaldolase-related protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.539
iolO
D-tagatose 3-epimerase-related protein; Catalyzes the reversible epimerization between 5-keto-L- gluconate (5-dehydro-L-gluconate) and D-tagaturonate, and thus probably functions in a myo-inositol degradation pathway together with IolG, IolM and IolN. Is not active on the enantiomer 5- keto-D-gluconate. Was also shown to be a nonphosphorylated sugar isomerase with broad substrate specificity in vitro. Is able to catalyze the reversible C3- epimerization of L-ribulose to L-xylulose, D-ribulose to D-xylulose, D- psicose to D-fructose, and D-tagatose to D-sorbose, with a substrate prefere [...]
 
  
  0.538
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
  
 
 0.476
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
 0.465
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
   
 0.431
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.