STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0308Alpha-xylosidase; Similar to PID:1881669 percent identity: 63.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 31 family. (764 aa)    
Predicted Functional Partners:
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
   
 
 0.837
TM_0310
beta-D-galactosidase; Similar to GB:L03424 PID:551691 percent identity: 68.26; identified by sequence similarity; putative.
 
 
 0.722
TM_0273
Fructose-bisphosphate aldolase; Similar to GB:AE000657 percent identity: 78.33; identified by sequence similarity; putative.
   
   0.606
TM_0630
Nucleotide sugar epimerase, putative; Similar to GB:AE000666 percent identity: 74.92; identified by sequence similarity; putative.
   
 
 0.606
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. Belongs to the ribonuclease III family.
   
   0.603
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.595
rpmF
Ribosomal protein L32; Similar to GB:AE000657 percent identity: 72.41; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL32 family.
    
   0.584
rpmB
Ribosomal protein L28; Similar to GB:AE000657 percent identity: 78.95; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
    
   0.584
rpmG
Ribosomal protein L33; Similar to SP:P35873 GB:Z11839 PID:407022 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.584
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
    
   0.584
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.