STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0308Alpha-xylosidase; Similar to PID:1881669 percent identity: 63.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 31 family. (764 aa)    
Predicted Functional Partners:
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
   
 
 0.790
TM_0996
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 72.37; identified by sequence similarity; putative.
    
 0.779
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
   
   0.734
TM_0310
beta-D-galactosidase; Similar to GB:L03424 PID:551691 percent identity: 68.26; identified by sequence similarity; putative.
 
 
 0.709
galA
Alpha-galactosidase; Hydrolyzes the short-chain alpha-galactosaccharides raffinose, melibiose and stachyose.
    
 0.647
TM_0076
Xylosidase; Similar to PID:2429092 percent identity: 98.07; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 3 family.
 
  
 0.587
TM_0305
Endoglucanase, putative; Similar to GP:3560020 percent identity: 55.11; identified by sequence similarity; putative.
 
   
 0.540
aglB
Cyclomaltodextrinase, putative; Is able to hydrolyze various linear maltooligosaccharides (maltotriose to maltoheptaose) and cyclomaltodextrins (CDs), to mainly glucose and maltose, by liberating glucose from the reducing end of the molecules. Shows a very weak activity on starch. Can neither hydrolyze maltose nor degrade pullulan, but rapidly hydrolyzes acarbose, a strong amylase and glucosidase inhibitor, to acarviosine and glucose. Belongs to the glycosyl hydrolase 13 family.
    
 0.506
TM_1848
Cellobiose-phosphorylase; Similar to GP:3184120 percent identity: 97.66; identified by sequence similarity; putative.
     
 0.482
TM_1650
Alpha-amylase, putative; Similar to SP:P14898 PID:2691 percent identity: 52.11; identified by sequence similarity; putative.
    
 0.472
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.