STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0325Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:X73124 SP:P39640 PID:414006 GB:AL009126 percent identity: 57.94; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (251 aa)    
Predicted Functional Partners:
TM_0326
Transcriptional regulator, RpiR family; Similar to SP:P46118 PID:881368 GB:U00096 PID:1736496 PID:1788159 percent identity: 56.94; identified by sequence similarity; putative.
    
  0.814
TM_0327
Phosphoglycerate dehydrogenase, putative; Similar to GB:Pyro_h percent identity: 68.84; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 
 0.804
TM_0324
Conserved hypothetical protein; Similar to GB:L42023 SP:P44993 PID:1006258 PID:1221144 PID:1205278 percent identity: 60.62; identified by sequence similarity; putative.
   
  0.803
TM_0798
Malonyl CoA-acyl carrier protein transacylase; Similar to SP:P71019 PID:1502420 GB:AL009126 percent identity: 64.24; identified by sequence similarity; putative.
 0.715
TM_0802
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.644
TM_0828
Sugar kinase, pfkB family; Similar to SP:P11099 GB:X14827 PID:46605 percent identity: 54.05; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.622
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
    
 0.608
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
  
 
 0.595
sbcD
Exonuclease, putative; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.562
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.551
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.