Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0325Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:X73124 SP:P39640 PID:414006 GB:AL009126 percent identity: 57.94; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (251 aa)    
Predicted Functional Partners:
TM_0327
Phosphoglycerate dehydrogenase, putative; Similar to GB:Pyro_h percent identity: 68.84; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 
 0.807
TM_0326
Transcriptional regulator, RpiR family; Similar to SP:P46118 PID:881368 GB:U00096 PID:1736496 PID:1788159 percent identity: 56.94; identified by sequence similarity; putative.
    
  0.805
TM_0324
Conserved hypothetical protein; Similar to GB:L42023 SP:P44993 PID:1006258 PID:1221144 PID:1205278 percent identity: 60.62; identified by sequence similarity; putative.
    
  0.798
TM_0798
Malonyl CoA-acyl carrier protein transacylase; Similar to SP:P71019 PID:1502420 GB:AL009126 percent identity: 64.24; identified by sequence similarity; putative.
 0.708
TM_0990
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 71.88; identified by sequence similarity; putative.
   
 0.676
TM_0802
3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.614
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
    
 0.534
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
   
 0.532
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
  
 
 0.512
TM_0328
m4C-methyltransferase; Similar to GB:AE000511 PID:2313355 percent identity: 58.37; identified by sequence similarity; putative; Belongs to the N(4)/N(6)-methyltransferase family.
       0.495
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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