STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0327Phosphoglycerate dehydrogenase, putative; Similar to GB:Pyro_h percent identity: 68.84; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)    
Predicted Functional Partners:
apgM
Phosphonopyruvate decarboxylase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
  
  0.992
TM_0325
Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:X73124 SP:P39640 PID:414006 GB:AL009126 percent identity: 57.94; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.804
TM_0326
Transcriptional regulator, RpiR family; Similar to SP:P46118 PID:881368 GB:U00096 PID:1736496 PID:1788159 percent identity: 56.94; identified by sequence similarity; putative.
      0.794
TM_0547
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 67.00; identified by sequence similarity; putative.
  
 0.780
TM_0751
Uridine kinase-related protein; Similar to GB:U00089 SP:P75217 PID:1673952 percent identity: 52.11; identified by sequence similarity; putative.
   
  0.774
TM_0324
Conserved hypothetical protein; Similar to GB:L42023 SP:P44993 PID:1006258 PID:1221144 PID:1205278 percent identity: 60.62; identified by sequence similarity; putative.
       0.717
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.642
TM_0328
m4C-methyltransferase; Similar to GB:AE000511 PID:2313355 percent identity: 58.37; identified by sequence similarity; putative; Belongs to the N(4)/N(6)-methyltransferase family.
 
     0.623
TM_0990
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 71.88; identified by sequence similarity; putative.
  
 
 0.555
aspC
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 66.22; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
 0.549
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.