STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0327Phosphoglycerate dehydrogenase, putative; Similar to GB:Pyro_h percent identity: 68.84; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)    
Predicted Functional Partners:
apgM
Phosphonopyruvate decarboxylase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
  
  0.959
TM_0325
Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:X73124 SP:P39640 PID:414006 GB:AL009126 percent identity: 57.94; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.807
TM_0326
Transcriptional regulator, RpiR family; Similar to SP:P46118 PID:881368 GB:U00096 PID:1736496 PID:1788159 percent identity: 56.94; identified by sequence similarity; putative.
      0.788
TM_0547
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 67.00; identified by sequence similarity; putative.
  
 
 0.727
TM_0324
Conserved hypothetical protein; Similar to GB:L42023 SP:P44993 PID:1006258 PID:1221144 PID:1205278 percent identity: 60.62; identified by sequence similarity; putative.
       0.723
TM_0328
m4C-methyltransferase; Similar to GB:AE000511 PID:2313355 percent identity: 58.37; identified by sequence similarity; putative; Belongs to the N(4)/N(6)-methyltransferase family.
 
     0.622
TM_0268
5-methyltetrahydrofolate S-homocysteine methyltransferase; Similar to GB:U00017 PID:466997 percent identity: 54.29; identified by sequence similarity; putative.
   
  
 0.561
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
 
 
 
 0.538
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.492
aspC
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 66.22; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
 
 0.485
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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