STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0342Permease, putative; Similar to GB:Pyro_h percent identity: 66.03; identified by sequence similarity; putative. (413 aa)    
Predicted Functional Partners:
TM_0339
Hypothetical protein; Identified by sequence similarity; putative.
 
     0.553
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
  0.510
TM_0344
Prephenate dehydrogenase; Similar to PID:1653053 percent identity: 49.42; identified by sequence similarity; putative.
    
  0.504
TM_0155
Chorismate mutase/prephenate dehydratase; Similar to GB:AE000782 percent identity: 80.45; identified by sequence similarity; putative.
  
 
 0.495
TM_0353
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 52.83; identified by sequence similarity; putative; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.484
TM_0341
Hypothetical protein; Identified by sequence similarity; putative.
       0.469
TM_0268
5-methyltetrahydrofolate S-homocysteine methyltransferase; Similar to GB:U00017 PID:466997 percent identity: 54.29; identified by sequence similarity; putative.
   
 
  0.452
aroF
Chorismate mutase, putative; Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
  
    0.445
aroKB
Shikimate kinase/3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; In the C-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
  
 0.427
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.417
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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