STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0370Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 92.41; identified by sequence similarity; putative; Belongs to the UPF0273 family. (253 aa)    
Predicted Functional Partners:
TM_0369
Conserved hypothetical protein; Similar to GB:L77117 PID:1499898 percent identity: 77.62; identified by sequence similarity; putative.
       0.810
TM_0987
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 78.97; identified by sequence similarity; putative.
  
     0.733
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
 
     0.700
TM_0988
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 69.40; identified by sequence similarity; putative.
  
     0.621
TM_1419
Myo-inositol-1-phosphate synthase-related protein; Similar to GB:AE000782 percent identity: 50.86; identified by sequence similarity; putative.
  
     0.552
argR
Arginine repressor; Regulates arginine biosynthesis genes.
       0.529
TM_1011
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 66.29; identified by sequence similarity; putative.
  
     0.486
TM_0230
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.78; identified by sequence similarity; putative.
  
     0.460
TM_1235
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 77.64; identified by sequence similarity; putative.
  
     0.442
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.