STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0384Anaerobic ribonucleoside-triphosphate reductase-related protein; Similar to SP:P07075 PID:15354 percent identity: 53.92; identified by sequence similarity; putative. (183 aa)    
Predicted Functional Partners:
TM_0385
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 52.27; identified by sequence similarity; putative.
  
 
 0.991
TM_0038
6-pyruvoyl tetrahydrobiopterin synthase, putative; Similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124 percent identity: 62.18; identified by sequence similarity; putative.
  
 
 0.894
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.851
TM_0386
Bacterioferritin comigratory protein/NADH dehydrogenase; Similar to PID:1651777 percent identity: 59.42; identified by sequence similarity; putative.
     
 0.666
TM_0383
NADH oxidoreductase, putative; Similar to GB:AE000666 percent identity: 74.44; identified by sequence similarity; putative.
     
 0.525
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.479
TM_1512
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.463
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.450
tgt
tRNA guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
     
 0.412
TM_0382
Repair endonuclease, putative; Similar to GB:L77117 PID:1592082 percent identity: 69.71; identified by sequence similarity; putative.
       0.408
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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