STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0399Response regulator; Similar to SP:Q44006 percent identity: 65.92; identified by sequence similarity; putative. (225 aa)    
Predicted Functional Partners:
TM_0400
Sensor histidine kinase; Similar to PID:1001613 PID:1001628 percent identity: 54.23; identified by sequence similarity; putative.
 0.977
TM_1654
Sensor histidine kinase HpkA; Similar to PID:1575578 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
 0.930
TM_0853
Sensor histidine kinase; Similar to PID:1575578 GB:AE000512 percent identity: 61.11; identified by sequence similarity; putative.
 0.913
TM_1258
Sensor histidine kinase, PhoR-related; Similar to GB:M23549 SP:P23545 PID:143331 PID:2293271 GB:AL009126 percent identity: 56.96; identified by sequence similarity; putative.
 
 0.880
TM_0127
Sensor histidine kinase; Similar to PID:2352098 percent identity: 54.13; identified by sequence similarity; putative.
 
 0.709
TM_1359
Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874 percent identity: 56.58; identified by sequence similarity; putative.
 
  
 0.693
TM_1184
pleD-related protein; Similar to PID:1652841 percent identity: 50.78; identified by sequence similarity; putative.
 
 0.617
cheY
Chemotaxis response regulator CheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity).
  
  
 0.593
TM_1665
Hypothetical protein; Identified by sequence similarity; putative.
  
 0.510
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.486
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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