STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0399Response regulator; Similar to SP:Q44006 percent identity: 65.92; identified by sequence similarity; putative. (225 aa)    
Predicted Functional Partners:
TM_0400
Sensor histidine kinase; Similar to PID:1001613 PID:1001628 percent identity: 54.23; identified by sequence similarity; putative.
 
  0.967
TM_1654
Sensor histidine kinase HpkA; Similar to PID:1575578 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
 0.919
TM_0853
Sensor histidine kinase; Similar to PID:1575578 GB:AE000512 percent identity: 61.11; identified by sequence similarity; putative.
 
  0.873
TM_1258
Sensor histidine kinase, PhoR-related; Similar to GB:M23549 SP:P23545 PID:143331 PID:2293271 GB:AL009126 percent identity: 56.96; identified by sequence similarity; putative.
 
 
  0.824
sigA
RNA polymerase sigma-A factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.702
TM_1359
Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874 percent identity: 56.58; identified by sequence similarity; putative.
  
  
 0.694
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.686
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.624
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.621
cheY
Chemotaxis response regulator CheY; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity).
  
  
 0.593
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.