close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0402Ammonium transporter; Similar to GB:AE000782 percent identity: 67.74; identified by sequence similarity; putative. (435 aa)    
Predicted Functional Partners:
TM_0403
Nitrogen regulatory protein P-II; Similar to GP:2735324 percent identity: 69.64; identified by sequence similarity; putative; Belongs to the P(II) protein family.
 0.999
TM_1788
Conserved hypothetical protein, GGDEF domain; Similar to GB:AE000657 percent identity: 60.13; identified by sequence similarity; putative.
 
      0.896
cheB
Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
     
 0.617
TM_0406
Keto/oxoacid ferredoxin oxidoreductase, gamma subunit, putative; Similar to GB:L77117 PID:1591240 percent identity: 59.77; identified by sequence similarity; putative.
     
 0.599
TM_0404
Deoxycytidylate deaminase, putative; Similar to GB:AE000782 percent identity: 74.00; identified by sequence similarity; putative.
       0.596
TM_0405
Keto/oxoacid ferredoxin oxidoreductase, beta subunit, putative; Similar to GB:L77117 PID:1591241 percent identity: 69.14; identified by sequence similarity; putative.
       0.596
TM_0407
Diacylglycerol kinase, putative; Similar to PID:1001103 PID:1001137 percent identity: 58.26; identified by sequence similarity; putative.
       0.596
TM_0409
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 58.61; identified by sequence similarity; putative.
     
 0.586
TM_0410
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 59.03; identified by sequence similarity; putative.
       0.573
glnA
Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under [...]
  
  
 0.569
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.