STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0422Conserved hypothetical protein; Similar to GP:3172553 percent identity: 56.37; identified by sequence similarity; putative. (304 aa)    
Predicted Functional Partners:
TM_0418
Sugar ABC transporter, periplasmic sugar-binding protein, putative; Similar to PID:1850900 GB:AE000512 percent identity: 47.11; identified by sequence similarity; putative.
 
     0.871
TM_0419
Sugar ABC transporter, permease protein; Similar to GB:AL009126 percent identity: 54.04; identified by sequence similarity; putative.
 
    0.811
TM_0420
Sugar ABC transporter, permease protein; Similar to GB:Pyro_h percent identity: 64.75; identified by sequence similarity; putative.
 
    0.804
TM_0415
Hypothetical protein; Identified by sequence similarity; putative.
 
 
 0.755
TM_0421
Sugar ABC transporter, ATP-binding protein; Similar to GB:Pyro_h percent identity: 71.03; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
       0.752
iolG
Dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of myo-inositol (MI) to 2-keto-myo-inositol (scyllo-inosose), and thus probably functions in a myo-inositol degradation pathway together with IolM, IolN and IolO. Has no activity with scyllo-inositol and much reduced activity (78-fold lower catalytic efficiency) with 1D-chiro-inositol. Belongs to the Gfo/Idh/MocA family.
 
 
 0.730
iolN
Creatinine amidohydrolase, putative; Catalyzes the ring-opening hydrolysis of 3-dehydro-scyllo- inosose (diketo-inositol) to 5-dehydro-L-gluconate, and thus probably functions in a myo-inositol degradation pathway together with IolG, IolM and IolO; Belongs to the creatininase superfamily.
 
 
  0.638
TM_0312
Conserved hypothetical protein; Similar to SP:Q04869 PID:984688 percent identity: 59.38; identified by sequence similarity; putative.
  
 
 0.545
TM_0425
Oxidoreductase, putative; Similar to GB:AL009126 percent identity: 48.08; identified by sequence similarity; putative.
  
 
 0.545
TM_0426
PHT4-related protein; Similar to GB:D13229 PID:295711 percent identity: 54.73; identified by sequence similarity; putative.
  
 
 0.545
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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