STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gldAGlycerol dehydrogenase; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions (By similarity). Belongs to the iron-containing alcohol dehydrogenase family. (364 aa)    
Predicted Functional Partners:
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
     
 0.992
glpK2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
     
 0.991
TM_1432
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 54.61; identified by sequence similarity; putative.
    
  0.991
glpK1
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
     
 0.917
TM_0920
Alcohol dehydrogenase, iron-containing; Similar to GB:AE000657 percent identity: 57.73; identified by sequence similarity; putative.
  
 
 0.449
TM_1742
nagD protein, putative; Similar to SP:P15302 GB:X14135 PID:42081 GB:U00096 PID:1651278 percent identity: 56.05; identified by sequence similarity; putative; Belongs to the HAD-like hydrolase superfamily.
  
 
 0.416
TM_0425
Oxidoreductase, putative; Similar to GB:AL009126 percent identity: 48.08; identified by sequence similarity; putative.
  
    0.412
TM_0426
PHT4-related protein; Similar to GB:D13229 PID:295711 percent identity: 54.73; identified by sequence similarity; putative.
  
    0.412
TM_0424
Conserved hypothetical protein; Similar to GB:L77117 PID:1591686 percent identity: 56.51; identified by sequence similarity; putative.
       0.411
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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