STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0427Oxidoreductase, putative; Similar to GB:AE000657 percent identity: 45.06; identified by sequence similarity; putative. (664 aa)    
Predicted Functional Partners:
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
  
 0.998
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
  
 0.998
TM_1216
NADH dehydrogenase, 49 kDa subunit, putative; Similar to GB:Pyro_h percent identity: 70.22; identified by sequence similarity; putative; Belongs to the complex I 49 kDa subunit family.
  
 
 0.955
TM_0428
Oxidoreductase, putative; Similar to GB:AE000782 percent identity: 49.25; identified by sequence similarity; putative.
 
 
 0.949
TM_0290
Citrate synthase; Similar to GB:AE000782 percent identity: 66.39; identified by sequence similarity; putative; Belongs to the citrate synthase family.
  
 0.909
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
  
 0.887
TM_0540
Fumarate hydratase, N-terminal subunit; Similar to GB:AE000657 percent identity: 62.92; identified by sequence similarity; putative.
  
 
 0.853
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
  
 
 0.845
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
  
 0.831
TM_0228
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 72.27; identified by sequence similarity; putative.
  
 
 0.824
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.