STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
mcp1Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. (656 aa)    
Predicted Functional Partners:
cheA
Chemotaxis sensor histidine kinase CheA; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
 
 0.967
TM_0718
Purine-binding chemotaxis protein; Similar to GB:M13462 SP:P07365 PID:145520 GB:U00096 PID:1736540 percent identity: 61.43; identified by sequence similarity; putative.
 
 0.951
cheW
Purine-binding chemotaxis protein; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.
 
 0.950
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 0.935
cheB
Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.931
cheD
Chemotaxis methylation protein; Deamidates glutamine residues on chemoreceptors (MCPs). CheD- mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase. In addition, demethylates methylated glutamate residues on chemoreceptors Mcp2 and Mcp4. Enhances the activity of CheC.
 
  0.848
TM_0427
Oxidoreductase, putative; Similar to GB:AE000657 percent identity: 45.06; identified by sequence similarity; putative.
  
    0.764
TM_0428
Oxidoreductase, putative; Similar to GB:AE000782 percent identity: 49.25; identified by sequence similarity; putative.
       0.762
TM_0425
Oxidoreductase, putative; Similar to GB:AL009126 percent identity: 48.08; identified by sequence similarity; putative.
       0.721
TM_0426
PHT4-related protein; Similar to GB:D13229 PID:295711 percent identity: 54.73; identified by sequence similarity; putative.
       0.721
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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