STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0437exo-poly-alpha-D-galacturonosidase, putative; Similar to GB:M31308 SP:P15922 PID:148447 percent identity: 49.48; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 28 family. (448 aa)    
Predicted Functional Partners:
TM_0436
Alcohol dehydrogenase, zinc-containing; Similar to PIR:S34613 percent identity: 51.75; identified by sequence similarity; putative.
    
  0.821
pelA
Pectate lyase; Cleaves unsaturated trigalacturonate from pectin. Activity is highest towards polygalacturonic acid, activity on methylated pectins decreases with an increasing degree of methylation.
 
  
 0.811
TM_0305
Endoglucanase, putative; Similar to GP:3560020 percent identity: 55.11; identified by sequence similarity; putative.
 
 0.778
TM_0440
Hypothetical protein; Identified by sequence similarity; putative.
       0.731
TM_0441
Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:AE000782 percent identity: 62.88; identified by sequence similarity; putative.
       0.731
TM_0439
Transcriptional regulator, GntR family; Similar to GB:AL009126 percent identity: 58.29; identified by sequence similarity; putative.
       0.730
TM_0438
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
       0.728
TM_0442
Conserved hypothetical protein; Similar to PID:609549 percent identity: 54.77; identified by sequence similarity; putative.
       0.700
TM_0443
Gluconate kinase; Similar to GB:J02584 SP:P12011 GB:D31629 PID:143015 PID:563932 percent identity: 59.31; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
       0.700
uxaC
Uronate isomerase, putative; Similar to SP:P42607 PID:606033 GB:U00096 PID:2367192 percent identity: 58.33; identified by sequence similarity; putative; Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
 
  
 0.679
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.