Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_04386-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (469 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 0.994
TM_0443
Gluconate kinase; Similar to GB:J02584 SP:P12011 GB:D31629 PID:143015 PID:563932 percent identity: 59.31; identified by sequence similarity; putative; Belongs to the FGGY kinase family.
    
 0.990
pgl
Oxidoreductase, sol/devB family; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.985
TM_1718
Ribulose-phosphate 3-epimerase; Similar to GB:L77117 SP:Q58093 PID:1591395 percent identity: 66.36; identified by sequence similarity; putative; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.977
TM_1080
Sugar-phosphate isomerase; Similar to GB:AE000657 percent identity: 77.62; identified by sequence similarity; putative.
    
 0.960
TM_1762
Transketolase, putative; Similar to GP:452486 percent identity: 53.52; identified by sequence similarity; putative.
  
 
 0.956
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
   
 
 0.948
tal
Transaldolase-related protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.933
TM_0441
Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GB:AE000782 percent identity: 62.88; identified by sequence similarity; putative.
  
 0.920
uxuA
D-mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
     
  0.876
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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