Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_0444Aspartate ammonia-lyase; Similar to GB:M63264 SP:P26899 PID:142518 PID:1303988 GB:AL009126 percent identity: 63.79; identified by sequence similarity; putative. (458 aa)    
Predicted Functional Partners:
aspC
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 66.22; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
     
 0.977
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
 0.972
purB
Adenylosuccinate lyase; Similar to GB:AE000657 percent identity: 73.60; identified by sequence similarity; putative.
     
 0.957
TM_1698
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 53.25; identified by sequence similarity; putative.
     
 0.957
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.956
pyrBI
Aspartate carbamoyltransferase, catalytic and regulatory chains; Similar to PID:1772605 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; In the N-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.954
TM_0547
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 67.00; identified by sequence similarity; putative.
    
 0.898
TM_0290
Citrate synthase; Similar to GB:AE000782 percent identity: 66.39; identified by sequence similarity; putative; Belongs to the citrate synthase family.
     
 0.889
argG
Argininosuccinate synthase; Similar to SP:P16460 PID:192065 PID:192066 PID:309111 PID:553871 percent identity: 76.79; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.888
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.886
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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