STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0448Hypothetical protein; Identified by sequence similarity; putative. (711 aa)    
Predicted Functional Partners:
TM_1735
Conserved hypothetical protein; Similar to PID:1001350 PID:1001356 percent identity: 50.28; identified by sequence similarity; putative.
 
  
 0.868
TM_1573
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 49.02; identified by sequence similarity; putative.
  
 
 0.848
TM_1575
Hypothetical protein; Identified by sequence similarity; putative.
  
 
 0.848
TM_0912
Basic membrane protein, putative; Similar to GB:AE000783 percent identity: 50.87; identified by sequence similarity; putative.
 
 
 0.847
TM_0890
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 59.04; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
 
  
 0.844
TM_1053
Cationic outer membrane protein; Similar to GB:M34854 SP:P31519 PID:155479 percent identity: 53.85; identified by sequence similarity; putative.
 
  
 0.820
thyX
Thy1 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant.
       0.819
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
       0.752
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.752
TM_1704
Hypothetical protein; Identified by sequence similarity; putative.
 
 
 0.741
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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