Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TM_0467Regulatory protein, putative; Similar to PID:1653310 percent identity: 53.02; identified by sequence similarity; putative. (445 aa)    
Predicted Functional Partners:
TM_1442
Anti-sigma factor antagonist, putative; In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition; Belongs to the anti-sigma-factor antagonist family.
 
 0.936
TM_0733
sigma-B regulator, putative; Similar to GP:2660754 percent identity: 49.59; identified by sequence similarity; putative.
 
 0.887
TM_1081
Anti-sigma factor antagonist, putative; In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition; Belongs to the anti-sigma-factor antagonist family.
 
 0.881
TM_0468
Response regulator; Similar to PID:1575577 GB:AE000512 percent identity: 69.17; identified by sequence similarity; putative.
  
 
 0.846
TM_0466
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 76.00; identified by sequence similarity; putative.
       0.817
TM_0469
Hypothetical protein; Identified by sequence similarity; putative.
       0.815
TM_0470
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 49.84; identified by sequence similarity; putative.
       0.813
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
    0.790
TM_0462
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.786
dnaE
DNA polymerase III, alpha subunit, putative; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity); Belongs to the DNA polymerase type-C family. DnaE subfamily.
       0.781
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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