STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0468Response regulator; Similar to PID:1575577 GB:AE000512 percent identity: 69.17; identified by sequence similarity; putative. (122 aa)    
Predicted Functional Partners:
TM_0853
Sensor histidine kinase; Similar to PID:1575578 GB:AE000512 percent identity: 61.11; identified by sequence similarity; putative.
 0.999
cheA
Chemotaxis sensor histidine kinase CheA; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
 
 0.955
TM_1654
Sensor histidine kinase HpkA; Similar to PID:1575578 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
 0.920
TM_0400
Sensor histidine kinase; Similar to PID:1001613 PID:1001628 percent identity: 54.23; identified by sequence similarity; putative.
 
 0.885
TM_1258
Sensor histidine kinase, PhoR-related; Similar to GB:M23549 SP:P23545 PID:143331 PID:2293271 GB:AL009126 percent identity: 56.96; identified by sequence similarity; putative.
 
 0.884
TM_0467
Regulatory protein, putative; Similar to PID:1653310 percent identity: 53.02; identified by sequence similarity; putative.
  
 
  0.850
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
    
 0.824
TM_0466
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 76.00; identified by sequence similarity; putative.
       0.820
TM_0470
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 49.84; identified by sequence similarity; putative.
     
 0.812
TM_0469
Hypothetical protein; Identified by sequence similarity; putative.
       0.810
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.