STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0481Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 59.38; identified by sequence similarity; putative. (382 aa)    
Predicted Functional Partners:
uvrA
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.810
secG
Hypothetical protein; Subunit of the protein translocation channel SecYEG.
       0.723
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
       0.695
TM_0482
(R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; Similar to GB:L77117 SP:Q58210 PID:1591496 percent identity: 53.49; identified by sequence similarity; putative.
 
     0.544
omp-alpha
Outer membrane protein alpha; Links the outer membrane to the inner membrane. Long fibrous protein that could serve to separate the two membranes.
       0.484
TM_0474
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.44; identified by sequence similarity; putative; Belongs to the NAPRTase family.
 
     0.430
TM_0476
Hypothetical protein; Identified by sequence similarity; putative.
       0.420
TM_1053
Cationic outer membrane protein; Similar to GB:M34854 SP:P31519 PID:155479 percent identity: 53.85; identified by sequence similarity; putative.
  
     0.408
TM_0600
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 55.93; identified by sequence similarity; putative.
  
     0.406
TM_0049
Iron-sulfur cluster-binding protein; Similar to GB:AE000666 percent identity: 56.54; identified by sequence similarity; putative.
  
     0.400
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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