STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prmChemK protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (282 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 0.994
TM_0852
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
  
 0.914
TM_1550
Conserved hypothetical protein; Similar to SP:P54515 PID:1303898 GB:AL009126 percent identity: 59.93; identified by sequence similarity; putative.
      0.907
TM_0487
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 69.00; identified by sequence similarity; putative.
       0.817
TM_0268
5-methyltetrahydrofolate S-homocysteine methyltransferase; Similar to GB:U00017 PID:466997 percent identity: 54.29; identified by sequence similarity; putative.
     
  0.769
TM_0483
ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 66.35; identified by sequence similarity; putative.
       0.556
TM_0484
Pyrimidine precursor biosynthesis enzyme, putative; Similar to SP:P42883 SP:P43534 SP:P47183 PID:1015913 PID:1302455 percent identity: 52.16; identified by sequence similarity; putative.
       0.556
TM_0485
ABC transporter, permease protein, cysTW family; Similar to GB:L42023 PID:1003598 PID:1222281 PID:1204605 SP:Q57306 percent identity: 52.16; identified by sequence similarity; putative.
       0.556
TM_0486
Conserved hypothetical protein; Similar to GB:U04966 PID:498839 percent identity: 72.63; identified by sequence similarity; putative.
       0.556
mnmE
Thiophene oxidation protein ThdF-related GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
   
 0.553
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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