Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_0494Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (167 aa)    
Predicted Functional Partners:
TM_0493
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.999
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.811
smc
Chromosome segregation SMC protein, putative; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.806
cmk
Cytidylate kinase; Similar to SP:P38493 GB:U11687 PID:533105 PID:1146214 GB:AL009126 percent identity: 68.18; identified by sequence similarity; putative.
 
  
 0.731
TM_0264
16S pseudouridylate synthase; Similar to SP:P33918 PID:405907 GB:U00096 PID:1788510 percent identity: 59.83; identified by sequence similarity; putative; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.655
TM_0491
Hypothetical protein; Identified by sequence similarity; putative.
       0.575
cobB
Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear.
       0.574
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
    0.546
TM_0445
Conserved hypothetical protein; Similar to PID:1001414 PID:1001399 percent identity: 52.55; identified by sequence similarity; putative.
  
  
 0.542
der
Conserved hypothetical protein; GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity). Has GTPase activity but no ATPase activity. GTP, GDP, and dGTP but not GMP, ATP, CTP, and UTP compete for GTP binding; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.542
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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