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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmungConserved hypothetical protein; Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA. Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. (192 aa)    
Predicted Functional Partners:
TM_0508
Conserved hypothetical protein; Similar to GP:2829884 percent identity: 63.36; identified by sequence similarity; putative; In the N-terminal section; belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
   
   0.859
TM_0510
Iron-dependent transcriptional repressor, putative; Similar to GP:2624310 percent identity: 62.63; identified by sequence similarity; putative.
       0.827
TM_0509
UDP-glucose 4-epimerase, putative; Similar to GB:L77117 SP:Q57664 PID:1590951 percent identity: 68.85; identified by sequence similarity; putative.
       0.810
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.739
def
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
    
 0.706
ssb
Single stranded DNA-binding protein, putative; Similar to GB:AE000657 percent identity: 57.14; identified by sequence similarity; putative.
   
   0.597
TM_0512
Hypothetical protein; Identified by sequence similarity; putative.
       0.562
tsaB
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
  
    0.557
TM_0128
Oxaloacetate decarboxylase, alpha subunit; Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 67.42; identified by sequence similarity; putative.
  
    0.512
TM_1365
Flagellar basal-body rod protein FlgC; Similar to PID:1165277 PID:1196316 SP:Q57466 GB:AE000783 percent identity: 72.46; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
    
   0.472
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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