STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0524Conserved hypothetical protein; Similar to SP:P54171 PID:1256637 GB:AL009126 percent identity: 64.15; identified by sequence similarity; putative. (254 aa)    
Predicted Functional Partners:
miaA
tRNA delta-2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
      0.933
hfq
Host factor I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
     0.766
hflX
Conserved hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.703
TM_0529
Heavy metal binding protein; Similar to GB:X73112 PID:483769 SP:Q51770 percent identity: 56.52; identified by sequence similarity; putative.
       0.668
TM_0534
RNA polymerase sigma-H factor, putative; Similar to GB:M29694 SP:P02964 PID:143542 percent identity: 58.24; identified by sequence similarity; putative; Belongs to the sigma-70 factor family.
 
     0.666
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.660
TM_0530
Oligopeptide ABC transporter, ATP-binding protein; Similar to SP:P42065 PID:677944 GB:AL009126 percent identity: 73.60; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
       0.639
TM_0531
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; Similar to GB:AE000657 percent identity: 60.12; identified by sequence similarity; putative.
       0.609
hslU
Heat shock protein HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
       0.559
TM_0806
Hypothetical protein; Identified by sequence similarity; putative.
 
     0.547
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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