STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0541Fumarate hydratase, C-terminal subunit; Similar to GB:AE000657 percent identity: 67.28; identified by sequence similarity; putative. (164 aa)    
Predicted Functional Partners:
TM_0540
Fumarate hydratase, N-terminal subunit; Similar to GB:AE000657 percent identity: 62.92; identified by sequence similarity; putative.
 
 0.999
TM_0542
Malate oxidoreductase; Similar to GP:1006839 percent identity: 70.94; identified by sequence similarity; putative.
 
 
 0.999
TM_0290
Citrate synthase; Similar to GB:AE000782 percent identity: 66.39; identified by sequence similarity; putative; Belongs to the citrate synthase family.
  
 
 0.950
TM_0427
Oxidoreductase, putative; Similar to GB:AE000657 percent identity: 45.06; identified by sequence similarity; putative.
  
 
 0.754
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
  
 
 0.587
trpB2
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.562
TM_0538
Cation efflux system protein; Similar to GB:Pyro_h percent identity: 81.18; identified by sequence similarity; putative; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.547
gcvPB
Glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
   
    0.519
TM_1148
Isocitrate dehydrogenase; Similar to SP:P21954 PID:1431074 PID:171749 percent identity: 74.63; identified by sequence similarity; putative; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
  
 0.486
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
     
 0.461
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.