STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0583Lipopolysaccharide biosynthesis protein; Similar to GB:Pyro_h percent identity: 71.97; identified by sequence similarity; putative; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (434 aa)    
Predicted Functional Partners:
TM_1034
UDP-N-acetylglucosamine 2-epimerase; Similar to GB:M87049 SP:P27828 GB:L18799 PID:148189 PID:304919 percent identity: 74.59; identified by sequence similarity; putative; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 
 0.996
TM_0610
Lipopolysaccharide biosynthesis protein; Similar to PID:992974 percent identity: 66.29; identified by sequence similarity; putative; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
 0.974
TM_0585
Lipopolysaccharide biosynthesis protein BplA; Similar to PID:992971 percent identity: 58.43; identified by sequence similarity; putative.
 
 
 0.963
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 
 0.931
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
  0.915
tilS
Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
  
 0.840
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
       0.810
TM_0581
Hypothetical protein; Identified by sequence similarity; putative.
       0.810
TM_0582
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 53.48; identified by sequence similarity; putative.
       0.810
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
 
 
 0.709
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.