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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0590Penicillin-binding protein 2; Similar to GB:AE000657 percent identity: 55.31; identified by sequence similarity; putative. (557 aa)    
Predicted Functional Partners:
TM_0839
Rod shape-determining protein RodA; Similar to GB:AE000657 percent identity: 63.05; identified by sequence similarity; putative; Belongs to the SEDS family.
 
 0.994
TM_0870
Penicillin-binding protein 2; Similar to SP:Q03524 GB:Z15056 PID:304166 PID:40161 PID:580936 percent identity: 52.23; identified by sequence similarity; putative.
  
  
 
0.993
TM_0233
Cell division protein, rodA/ftsW/spoVE family; Similar to GB:AE000511 SP:P56096 PID:2314744 percent identity: 58.44; identified by sequence similarity; putative; Belongs to the SEDS family.
 
 0.971
TM_0588
Rod shape-determining protein MreB; Similar to SP:Q01465 percent identity: 77.06; identified by sequence similarity; putative.
 
 0.879
TM_1544
Rod shape-determining protein MreB; Similar to SP:P32444 GB:X62374 PID:49005 percent identity: 74.61; identified by sequence similarity; putative.
 
 0.858
TM_0886
Penicillin-binding protein, class 1A; Similar to GP:1763284 percent identity: 55.64; identified by sequence similarity; putative.
 
 
 0.829
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.733
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of both L- and D-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use meso-diaminopimelate as the amino acid substrate in vitro, although much less efficiently; Belongs to the MurCDEF family. MurE subfamily.
  
 0.709
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.707
ddl
D-alanine--D-alanine ligase; Cell wall formation.
 
 
 0.644
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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