Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_0593Amino acid ABC transporter, periplasmic amino acid-binding protein; Similar to GB:AE000782 percent identity: 64.68; identified by sequence similarity; putative. (246 aa)    
Predicted Functional Partners:
TM_0592
Amino acid ABC transporter, permease protein; Similar to GB:AE000782 percent identity: 72.86; identified by sequence similarity; putative.
 0.999
TM_0591
Amino acid ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 80.08; identified by sequence similarity; putative.
 0.996
TM_0155
Chorismate mutase/prephenate dehydratase; Similar to GB:AE000782 percent identity: 80.45; identified by sequence similarity; putative.
    
 0.766
TM_0594
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57772 PID:1591045 percent identity: 76.92; identified by sequence similarity; putative.
       0.651
TM_0595
Sugar ABC transporter, periplasmic sugar-binding protein, putative; Similar to SP:P10904 GB:U00039 GB:M33735 PID:43244 PID:466589 percent identity: 48.57; identified by sequence similarity; putative.
  
  
 0.542
TM_1359
Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874 percent identity: 56.58; identified by sequence similarity; putative.
    
 0.510
aroKB
Shikimate kinase/3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; In the C-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
     
 0.461
argG
Argininosuccinate synthase; Similar to SP:P16460 PID:192065 PID:192066 PID:309111 PID:553871 percent identity: 76.79; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.405
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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