STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0648Conserved hypothetical protein; Similar to GB:L77117 SP:Q58774 PID:1592331 percent identity: 59.42; identified by sequence similarity; putative. (132 aa)    
Predicted Functional Partners:
TM_0649
Hypothetical protein; Identified by sequence similarity; putative.
 
     0.948
ispF
Conserved hypothetical protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.780
TM_0646
Hypothetical protein; Identified by sequence similarity; putative.
       0.773
TM_1000
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57607 PID:1590904 percent identity: 61.34; identified by sequence similarity; putative; Belongs to the UPF0332 family.
 
     0.690
TM_1001
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57606 PID:1498910 percent identity: 65.43; identified by sequence similarity; putative.
  
     0.593
nadE1
NH(3)-dependent NAD(+) synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.565
TM_0644
Hypothetical protein; Identified by sequence similarity; putative.
       0.526
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.