STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0652Conserved hypothetical protein; Similar to GP:2444077 percent identity: 54.90; identified by sequence similarity; putative. (286 aa)    
Predicted Functional Partners:
miaB
Conserved hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
 
 
   0.838
TM_0651
Conserved hypothetical protein; Similar to PID:1653547 percent identity: 52.43; identified by sequence similarity; putative.
     
 0.832
TM_0650
Hypothetical protein; Identified by sequence similarity; putative.
       0.818
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. It has lower affinity and lower activity towards 1,3-diaminopropane, cadaverine (1,5-diaminopentane), agmatine, norspermidine and spermidine (in vitro).
     
 0.578
speH
Conserved hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
       0.570
TM_1693
1-acyl-sn-glycerol-3-phosphate acetyltransferase, putative; Similar to GB:L32861 PID:520780 GB:AE000783 percent identity: 57.75; identified by sequence similarity; putative; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
  
 0.552
TM_1861
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Similar to SP:P46322 PID:893358 PID:1842439 GB:AL009126 percent identity: 60.87; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.543
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
     
 0.540
TM_0656
Conserved hypothetical protein; Similar to SP:P38522 GB:U00096 PID:1742120 PID:1742129 PID:1787557 percent identity: 56.60; identified by sequence similarity; putative.
       0.521
cdsA
Phosphatidate cytidylyltransferase, putative; Similar to GB:AL009126 percent identity: 55.00; identified by sequence similarity; putative.
     
 0.511
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.