Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0657Rubrerythrin; Similar to GB:AE000782 percent identity: 74.55; identified by sequence similarity; putative. (170 aa)    
Predicted Functional Partners:
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
  
 
 0.953
TM_0658
Neelaredoxin; Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
 
  
 0.929
TM_0659
Rubredoxin; Similar to GB:M60116 SP:P00268 PID:144909 percent identity: 83.02; identified by sequence similarity; putative.
  
  
 0.868
TM_0807
Alkyl hydroperoxide reductase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.582
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
  
 
 0.517
TM_0201
NADP-reducing hydrogenase, subunit D, putative; Similar to GB:U07229 PID:466366 percent identity: 69.31; identified by sequence similarity; putative.
    
 0.493
TM_1426
Fe-hydrogenase, subunit alpha; Similar to GP:2865517 percent identity: 100.00; identified by sequence similarity; putative.
    
 0.493
TM_0755
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 74.19; identified by sequence similarity; putative.
 
  
 0.479
TM_0228
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 72.27; identified by sequence similarity; putative.
    
 0.462
TM_0660
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 60.24; identified by sequence similarity; putative.
       0.461
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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