STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0703Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. (408 aa)    
Predicted Functional Partners:
TM_1861
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Similar to SP:P46322 PID:893358 PID:1842439 GB:AL009126 percent identity: 60.87; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.989
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.955
TM_0474
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.44; identified by sequence similarity; putative; Belongs to the NAPRTase family.
  
 
 0.953
TM_1645
Nicotinate-nucleotide pyrophosphorylase; Similar to GB:AE000666 percent identity: 62.13; identified by sequence similarity; putative; Belongs to the NadC/ModD family.
    
 0.947
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
      0.900
TM_1648
Conserved hypothetical protein; Similar to SP:P54456 PID:1303792 GB:AL009126 percent identity: 57.92; identified by sequence similarity; putative.
    
 0.897
surE
Stationary phase survival protein; Nucleotidase that preferentially dephosphorylates 5'-GMP and 5'-AMP.
    
  0.895
TM_1878
UDP-sugar hydrolase; Similar to SP:P07024 PID:757842 GB:U00096 PID:1773162 PID:1786687 percent identity: 62.97; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family.
  
 
  0.889
TM_1742
nagD protein, putative; Similar to SP:P15302 GB:X14135 PID:42081 GB:U00096 PID:1651278 percent identity: 56.05; identified by sequence similarity; putative; Belongs to the HAD-like hydrolase superfamily.
  
 
  0.874
mazG
mazG protein; Catalyzes the hydrolysis of all eight canonical ribonucleoside triphosphates (NTP) and deoxyribonucleoside triphosphates (dNTP) to their corresponding nucleoside monophosphates ((d)NMP) and PPi and subsequently hydrolyzes the resultant PPi to Pi. The NTPase activity with deoxyribonucleoside triphosphates as substrate is higher than corresponding ribonucleoside triphosphates. dGTP is the best substrate among the deoxyribonucleoside triphosphates, and GTP is the best among the ribonucleoside triphosphates.
     
  0.871
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.