STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0717propionyl-CoA carboxylase, gamma subunit; Similar to GP:2706400 percent identity: 51.91; identified by sequence similarity; putative. (134 aa)    
Predicted Functional Partners:
TM_0880
Oxaloacetate decarboxylase, beta subunit; Similar to GB:AE000782 percent identity: 74.01; identified by sequence similarity; putative.
 
  
  0.994
TM_0224
biotin--(acetyl-CoA carboxylase) synthetase; Similar to GB:AE000666 percent identity: 57.33; identified by sequence similarity; putative.
 
 
 0.977
TM_0716
propionyl-CoA carboxylase, beta subunit; Similar to PID:1177652 SP:P53003 percent identity: 76.31; identified by sequence similarity; putative.
 
 0.965
TM_0128
Oxaloacetate decarboxylase, alpha subunit; Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 67.42; identified by sequence similarity; putative.
 
  
 0.788
TM_0718
Purine-binding chemotaxis protein; Similar to GB:M13462 SP:P07365 PID:145520 GB:U00096 PID:1736540 percent identity: 61.43; identified by sequence similarity; putative.
       0.773
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.745
cysS
cysteinyl-tRNA synthetase; Similar to GB:AE000657 percent identity: 69.26; identified by sequence similarity; putative; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.729
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.717
rnr
vacB protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
    0.685
TM_0724
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 64.33; identified by sequence similarity; putative.
       0.685
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.